

邢蒙恩
simonxing@wmu.edu.cn
1、 个人简介:
专注于阿尔茨海默病和自闭症的致病机制研究,聚焦“阿尔茨海默病的分子致病机制研究”和“自闭症的致病风险基因”,探索相关风险基因在以上疾病中的致病机理,探索临床转化的价值,致力于为阿尔茨海默病和自闭症的治疗靶标发现和药物研发提供新思路和新策略。
2、 研究方向:
阿尔茨海默病和自闭症的致病机制及转化治疗研究
3、 参与项目:
1. 国家自然科学基金,青年项目, 2024-01至2026-12,在研,主持
2. 中国博士后科学基金面上项目,2019M652254,结题,主持
3. 国家自然科学基金,重大项目, 2023-01至2027-12,在研,参与
4、 代表论著:
1. Mengen Xing# and Weihong Song. Engineering Aβ-antibody for safer and more effective Alzheimer’s immunotherapy, Science, 2025.
2. Mengen Xing#; Wanqi Chen#; Yachen Ji; Weihong Song. SLC44A2-mediated phenotypic switch of vascular smooth muscle cells contributes to aortic aneurysm, The Journal of Clinical Investigation, 2024.
3. Qing Zhang#; Mengen Xing#; et al., Contactin-associated protein-like 2 (CNTNAP2) mutations impair the essential α-secretase cleavages, leading to autism-like phenotypes, Signal Transduction and Targeted Therapy, 2024.
4. Mengen Xing#; Qing Zhang#; Weihong Song. GIGYF1-disturbed IGF-1R recycling: a potential contributor to autism spectrum disorder pathogenesis, The Journal of Clinical Investigation, 2022.
5. Keenan Sterling#; Mengen Xing#; Weihong Song; Do Systemic Infections Contribute to the Pathogenesis of Dementia, Neuroscience Bulletin, 2021.
6. Mengen Xing#; et al., A Sialic Acid-Binding Protein SABP1 of T. gondii Mediates Host Cell Attachment and Invasion, Journal of Infectious Diseases, 2020.